Signature Serum

✓ 95% agreed skin felt soothed

The hero of the Dr Somji system. A multi-active daily antioxidant serum built around SOM1X®, our proprietary barrier-strengthening complex, to keep skin stable, supported and performing at its best.

Hydrating

RADIANCE-BOOSTING

RESILIENCE-BUILDING

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Your skin isn't the same every day. It shifts with stress, hormones, the seasons, the products around it. What it needs is something consistent underneath all of that, a daily foundation it can rely on. That's what the Signature Serum was designed to be.

  • At the centre of the formula is SOM1X® — our proprietary complex developed exclusively with the Dr MediSpa clinical team. SOM1X® works at the level of the skin barrier: strengthening its structure, reducing moisture loss and supporting the skin's ability to regulate itself over time.

  • As part of the Dr Somji Protocol, it's formulated to be layered over any of our targeted Concentrates, amplifying their results and allowing you to personalise your routine as your skin's needs evolve.

  • Pure Beauty 2024 — Best New Dermatological Treatment or Product. Formulated by Dr Munir Somji, Cosmetic Surgeon and Co-Founder of the award-winning Dr MediSpa Clinics.

  • 95% agree skin feels soothed
  • 90% said skin feels hydrated
  • 88% said skin feels moisturised
  • 87% agreed skin felt nourished

SOM1X®

Dr Somji's proprietary barrier-repair complex. Strengthens the skin barrier, reduces moisture loss and
supports long-term skin health.

Green Tangerine Exosomes

Biological nanoparticles sourced from Jeju Island, Korea. Higher Vitamin C content than lemons; rich in
anti-inflammatory Nobiletin. Drive hydration and renewal deeper into the skin, increasing Elastin and Hyaluronic Acid production.

Encapsulated Retinol

Controlled-release delivery, reducing irritation while maximising bioavailability. Increases Collagen 1 and
Elastin content, improving firmness and reducing fine lines.

Probiotics

Regulate microbiota pathways and restore the skin's instinctive defences.

Ceramides

Skin-identical ceramides in a bio-mimetic matrix. Repair and restore the protective skin barrier, enhancing
moisture and smoothness.

Encapsulated Multivitamins

Stabilised Vitamins F, A, C and E delivered to deeper skin layers. Battles oxidative stress and the appearance of premature ageing.

Aqua (Water), Propylheptyl Caprylate, Glycerin, Passiflora Edulis Seed Oil, Octyldodecanol, Inulin Lauryl Carbamate, Dimethyl Sulfone, Rosa Canina Fruit Oil, Xanthan Gum, Sorbitol, Sodium Pca, Maltodextrin, Copernicia Cerifera (Carnauba) Wax, Helianthus Annuus (Sunflower) Seed Oil, Sodium Lactate, Maris Aqua (Sea Water), Ribes Nigrum (Black Currant) Seed Oil, Citrus Reticulata (Tangerine) Fruit Extract, Citrus Reticulata (Tangerine) Fruit Juice Vesicles, Madecassoside, Lecithin, Retinol, Retinyl Palmitate, Ceramide Np, Ceramide Ap, Ceramide Eop, Tocopherol, Lactobacillus Ferment, Tocopheryl Acetate, Pogostemon Cablin Leaf Extract, Behenic Acid, Cholesterol, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Carnosine, Rosmarinus Officinalis (Rosemary) Leaf Extract, 3-O-Ethyl Ascorbic Acid, Phytosphingosine, Laminaria Digitata Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Chondrus Crispus (Carrageenan) Extract, Chlorella Vulgaris Extract, Silybum Marianum Fruit Extract, Humulus Lupulus (Hops) Extract, Phenoxyethanol, Magnesium Aluminum Silicate, Caprylyl Glycol, Citronellyl Methylcrotonate, Polysorbate 20, Propanediol, Ethylhexylglycerin, Phytic Acid, Glyceryl Linoleate, Glyceryl Stearate, Glyceryl Linolenate, 1,2-Hexanediol, Glucose, Disodium Cocoamphodiacetate, Dehydroacetic Acid, Polyglyceryl-10 Stearate, Cetearyl Alcohol, Sodium Levulinate, Polyglyceryl-6 Behenate, Potassium Sorbate, Saccharide Isomerate, Triethyl Citrate, Ethyl Ferulate, Sodium Cetearyl Sulfate, Benzyl Alcohol, Benzoic Acid

What is SOM1X® and what makes it different?

SOM1X® is a proprietary barrier-repair complex developed exclusively by Dr Munir Somji and the Dr MediSpa clinical team. It works at the level of the skin's protective barrier — reinforcing its structure, reducing transepidermal moisture loss and supporting the skin's ability to regulate itself. What makes it particularly effective is its relationship with Encapsulated Retinol: by strengthening the barrier first, SOM1X® creates the environment for retinol to work at clinically active concentrations even on sensitive skin.

Can I use this if I have sensitive or reactive skin?

Yes. The Signature Serum is dermatologically tested and formulated to be suitable for sensitive skin. The encapsulated retinol in the formula is time-released to minimise irritation. If you have a significantly compromised barrier, consider using the Exosome Barrier Repair Serum first to build tolerance before introducing the Signature Serum.

When do I apply the Signature Serum in my routine?

Apply the Signature Serum as the second step, after your Concentrate (if using one) and before your SPF moisturiser in the morning, or Night Recovery Cream in the evening. It is designed to be layered over any of the four Concentrates — Anti-Wrinkle, Anti-Blemish, Anti-Redness, or Anti-Dark Spot.

Can I use the Signature Serum morning and evening?

Yes. It is formulated for twice-daily use. In the morning, follow with the Vitamin C Daily Defence SPF30. In the evening, follow with the Night Recovery Cream.

How long until I see visible results?

95% of trial participants reported soothed skin and 90% reported improved hydration within the 4-week trial period. Most users notice improved radiance and skin texture within 2–3 weeks. For firmness and barrier improvements, 4–8 weeks of consistent daily use is recommended.

Is this suitable for use during pregnancy?

The formula contains Encapsulated Retinol. We recommend consulting your GP or dermatologist before using retinol-containing products during pregnancy or breastfeeding.

Apply directly to cleansed face, neck and décolleté once or twice daily. If using a Concentrate, apply the Concentrate first, then follow with Signature Serum directly over the top.

Buy it with

 
Dr Somji Skincare

Dermatologically Tested

Dr Somji Skincare

Doctor Developed

Dr Somji Skincare

  Made in the UK

Dr Somji Skincare

Fragrance Free

Dr Somji Skincare

Cruelty Free

ACTIVE INGREDIENTS

Sourced from Jeju Island green tangerines — which contain more Vitamin C than lemons — these plant-derived biological nanoparticles penetrate the dermis to directly increase Elastin and Hyaluronic Acid production, redefining what topical hydration can achieve.

Using micro-encapsulation technology, retinol is time-released into the skin — bypassing surface irritation while delivering full bioavailability at depth. Clinically shown to increase Collagen 1 and Elastin for visible firmness and texture improvement.

A precision strain probiotic complex that rebalances the skin's microbiome at a genomic level — regulating the inflammatory pathways that drive sensitivity, dullness and accelerated ageing.

 PROPRIETARY BARRIER TECHNOLOGY

SOM1X®

Centella Leaf Extract, Marine Probiotics, Ceramides, MSM, Blackcurrant Seed Oil and Milk Thistle Extract work together to reinforce the skin's protective barrier, reduce moisture loss and support the skin's ability to regulate itself. Uniquely, SOM1X® creates the ideal environment for Encapsulated Retinol to deliver clinically active results — even on sensitive skin.

INDEPENDENT USER TRIALS

PROVEN RESULTS

95%

Agree skin feels soothed

90%

Said skin feels hydrated

88%

Said skin feels moisturised

OVERALL IMPROVEMENT IN SKIN QUALITY

VISIA imaging at 12 weeks shows firmer, brighter skin with improved evenness in both tone and texture.

COMPLETE YOUR ROUTINE

Targeted retinol and peptide treatment for fine lines.

The complete 5-step anti-ageing system.

Calm redness and rosacea with clinical exosome technology.

 
 
 

WHAT OUR CUSTOMERS SAY

"Gave my skin a radiance and glow"

"My skin looks and feels better and brighter"

"Makeup glides on nicely after use"

PRESS & EXPERT REVIEWS

"A lit-from-within glow I've never found in active skincare — and it acts as a beautiful face primer."

— Dani Guinsberg, Celebrity Makeup Artist

"I love the Signature Serum and the Vitamin C Daily Defence layered together — hydration, antioxidants, Vitamin C and sunscreen in just two products." 

— Sandra Cooke, Celebrity Makeup Artist

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