Exosome Barrier Repair Serum

✓ 95% said skin felt nourished and hydrated

An advanced barrier repair serum using Water Radish Exosomes — selected from over 50 plant exosomes for their unique similarity to human skin — plus Triple Ceramides and Hexapeptides. Perfect for post-procedure skin.

Restoring

Resilience Building

Regenerative

Size 50ml
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Free samples with every order

FREE UK SHIPPING OVER £60

Skin barrier compromise isn't always obvious. Sometimes it's dry, tight skin that never stays hydrated. Sometimes it's sudden sensitivity to products that never used to cause a reaction. Sometimes it's a feeling that your skin is just... fragile.

  • This serum was developed in the Dr MediSpa clinics after observing that a large proportion of patients had damaged skin barriers, often from overuse of active ingredients, mixing too many products, or harsh routines. During development, over 50 different plant exosomes were evaluated for compatibility with human skin. Water Radish exosomes share 48 DNA and mRNA transcripts with human skin barrier signalling pathways, more than any other plant exosome tested.

  • Dr Somji: "Next-generation skin barrier repair using exosome regenerative technology." 

  • Perfect for use post-procedure to speed up the healing time.
  • Formulated by Dr Munir Somji, Cosmetic Surgeon and Co-Founder of the award-winning Dr MediSpa Clinics.

Independent consumer user trial, 60 participants, 4 weeks:

  • 95% said skin felt nourished and hydrated — first use
  • 97% agree skin feels moisturised
  • 95% agree skin feels hydrated
  • 92% agree skin is healthy-looking
  • 90% agree skin feels soothed and smoothed
  • 88% agree skin looks radiant
  • 85% agree skin feels protected

Water Radish (Kimchi) Exosomes

Selected after evaluating over 50 plant exosomes. Share 48 DNA and mRNA transcripts with human skin barrier signalling pathways — more than any other plant exosome tested. Support skin repair and regeneration more effectively as a result.

Triple Ceramide Blend

All three essential ceramides (1, 3 and 6-II). Rebuilds the lipid barrier, reduces transepidermal water loss and restores hydration retention.

Olive Ceramides

Dermo-mimetic ceramide from olives. Improves skin elasticity and restores the skin's natural barrier.

Hexapeptides

Multi-tasking peptide to reverse signs of ageing, minimise fine lines, boost elasticity, firmness and radiance. Supports the skin's natural repair mechanisms.

Oat Kernel Extract

Natural lipid complex rich in skin-identical fatty acids. Leaves skin soothed and moisturised.

Pine Bark Phytosterols

Mimics lipids naturally present in the skin. Reduces visible redness and helps restore the skin barrier function.

Aqua (water), canola oil, glycerin, squalane, helianthus annuus (sunflower) seed oil unsaponifiables, passiflora edulis seed oil, lactobacillus ferment, avena sativa (oat) kernel oil, triolein, inulin lauryl carbamate, phytosterols, sodium PCA, ceramide NP, ceramide AP, ceramide EOP, acetyl hexapeptide-8, helianthus annuus (sunflower) seed oil, pogostemon cablin leaf extract, rosmarinus officinalis (rosemary) leaf extract, chondrus crispus (carrageenan) extract, sorbitol, cholesterol, behenic acid, sodium lactate, sodium levulinate, phytosphingosine, saccharide isomerate, magnesium aluminum silicate, caprylyl glycol, glyceryl dioleate, ethylhexylglycerin, polyglyceryl-10 stearate, triethyl citrate, polyglyceryl-6 behenate, cetearyl alcohol, phytic acid, glyceryl stearate, glucose, potassium sorbate, citric acid, sodium citrate, sodium benzoate, sodium cetearyl sulfate, octyldodecanol, xanthan gum, phenoxyethanol, 1,2-hexanediol.

What is a skin barrier and how do I know if mine is compromised?

The skin barrier is the outermost layer of the skin — a lipid matrix that retains moisture and protects against external aggressors. Signs of a compromised barrier include: persistent dryness and tightness that doesn't respond to moisturisers, sudden sensitivity to products that previously caused no reaction, redness, flaking, and a feeling of skin being 'reactive' or 'fragile'. If several of these apply, your barrier likely needs targeted repair rather than hydration alone.

Why Water Radish exosomes specifically?

During the development of this serum, the Dr MediSpa clinical team evaluated over 50 different plant exosomes for compatibility with human skin barrier cells. Water Radish exosomes were selected because they share 48 DNA and mRNA transcripts with human skin barrier signalling pathways — the highest genomic compatibility of any plant exosome tested. This allows them to communicate directly with and activate the skin's own repair mechanisms.

Is this suitable for post-procedure use after laser, microneedling or peels?

Yes — this is a core recommendation for post-procedure skin in the Dr MediSpa clinics. The combination of Water Radish Exosomes (barrier signalling), Triple Ceramides (lipid matrix reconstruction) and Oat Kernel Extract (soothing) provides the foundational support compromised post-procedure skin needs.

Can I use this alongside active ingredients like retinol or acids?

Yes. This serum is specifically designed to be used alongside — and to support the tolerability of — active ingredients. By repairing and strengthening the barrier, it allows the skin to handle actives that would otherwise cause irritation. Use it before the Night Recovery Cream in your evening routine.

How is this different from a standard barrier-repair moisturiser?

Most barrier-repair moisturisers work passively — they occlude and hydrate. The Exosome Barrier Repair Serum uses Water Radish Exosomes to actively communicate with the skin's own repair pathways at a genomic level, triggering barrier regeneration rather than just surface protection. The Hexapeptide complex also provides progressive collagen and elastin support, making it a treatment serum as well as a repair product.

Which skin types is this most suitable for?

Dry, sensitive, barrier-compromised, rosacea-prone, mature and post-procedure skin. It is suitable for all skin types experiencing barrier dysfunction, but is particularly recommended for those who have been overdoing active ingredients, have experienced a skin reaction, or are in recovery from an aesthetic treatment.

Apply directly to cleansed face, neck and décolleté once or twice daily. Follow with moisturiser. Can also be layered between your Concentrate and Signature Serum.

Buy it with

 
Dr Somji Skincare

Dermatologically Tested

Dr Somji Skincare

Doctor Developed

Dr Somji Skincare

  Made in the UK

Dr Somji Skincare

Fragrance Free

Dr Somji Skincare

Cruelty Free

ACTIVE INGREDIENTS

Selected from a panel of 50+ plant exosomes after full genomic mapping — Water Radish exosomes share 48 DNA and mRNA transcripts with human skin barrier cells, giving them an unmatched ability to communicate with and activate the skin's own repair signalling pathways.

The three ceramide species that together constitute the primary lipid matrix of the stratum corneum — delivering a structurally complete barrier reconstruction that single-ceramide formulas simply cannot achieve.

A multi-mechanism repair peptide that simultaneously inhibits acetylcholine-driven micro-contractions, stimulates type I and III collagen synthesis, and activates fibroblast proliferation — providing both immediate barrier support and progressive structural skin renewal.

INDEPENDENT USER TRIALS

PROVEN RESULTS

95%

said skin felt nourished and hydrated

90%

said skin feels soothed and smoothed

80%

skin looks radiant and feels protected

IMPROVED BARRIER & SKIN QUALITY

VISIA imaging at 8 weeks shows smoother, more even and less reactive skin, reflecting a better-supported barrier.

COMPLETE YOUR ROUTINE

A 100%-stripped-barrier-free cleanse to start every routine.

Overnight retinol renewal and barrier repair while you sleep.

The complete 3-step barrier repair system.

 
 
 
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WHAT OUR CUSTOMERS SAY

"No problems to my sensitive skin — in fact, my skin feels better than ever"

"Firmer. Younger looking skin"

"Cleared up dry patches and I've got nicer than usual soft skin"

PRESS & EXPERT REVIEWS

"Triple threat of Ceramides, Exosomes and Peptides — leaves clients' skin calm, nourished, soothed and glowing."  — Lucia Ferrari, Beauty Journalist, The Telegraph & Daily Mail

“A well formulated barrier repair moisturiser – this gets the GH thumbs up!” Good Housekeeping

  • 5 stars: 18 (100%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
L
L C.

My skin's barrier was severely comprised and this has gradually and carefully restored it.

A
Anonymous

light but gives plenty of moisture. Perfect as makeup base.

M
Marija

I have very acne prone skin and then repaired my skin barrier. It lasts for a long time and you don’t need much of the product. It’s the only thing that soothes my skin.

A
Anonymous

I think it does what it says on the tin. I tend to have slightly oily T zone and dry cheeks. After using the serum for nearly two months this difference has diminished. And it feels like I’m more of a normal skin type now. The cheeks are definitely less dry. I have been using it together with the vitamin c daily moisturiser which is also lovely, keeps your skin moist all day but it doesn’t feel heavy! Highly recommended!

D
D.

I have very sensitive dehydrated rosacea skin - this product has been amazing! I’ve repurchased 3 times, it calms my redness and my skin feels super hydrated and healthy! Great base to make up too - thank you for creating this excellent product :)

A
Anonymous

Exactly what my skin care was missing . All the richness without the heavy pore blocking. My skin is healing from the inside out. Love these products

E
Elle

Wonderful product. I have been using this now for 6 months and I am obsessed! It has given my skin the glow it’s been craving.

L
Lara

Absolutely love this! Works really well on my dry skin

A
Anonymous

Leaves skin feeling hydrated, soothed and plumped!

Y
Yousra

This serum has completely transformed my skin. From the first few uses, my skin felt stronger, calmer, and deeply hydrated. I’ve struggled with sensitivity and a compromised skin barrier, and this serum made a noticeable difference in how healthy and balanced my skin looks.

If you’re looking to repair, protect, and strengthen your skin barrier, this serum is a must have. Truly impressive results!

M
Mariana

My saviour!! it saved my skin so many times when i used too many actives or whenever i compromise my skin barrier, lightweight and nourishing

C
C.

This product has transformed my skin! I have had so many compliments on the glow. Its the holy grail!!!!

K
K.R.

This product transformed my skin in a matter of weeks, I use it mixed with the Vitamin C SPF as a primer to my make up and it’s a game changer!

N
Nicole G.

This has been brilliant for my skin and has also helped with some eczema I had underneath my eyes.

K
Katya T.

Relatively new to the range and therefore to me the barrier repair serum seems to double down on protecting the skin and I look forward to evaluating its results over a longer period of time. I am confident that as part of the Dr Somji range it provides an extra service to the skin in addition to the other products in the range.

S
SBP

I think this is really making a difference or my eyesight is getting worse! But people have been telling me that my skin looks great and my forehead lines seem to be less... coincidence? I think not. Now need to try the whole range!

S
Savva

Wow! what a product, nothing like i've ever used before. Deeply hydrating, and noticeably smoother after just 1 week. The texture is silky yet lightweight, absorbing beautifully without any greasy residue.

H
Helena

I love how this instantly plumps my skin and gives a lovely subtle glow. It makes my skin look smoother in general and I feel like long term, my skin is in so much better condition now, as I usually suffer from a lot of redness and dry flaky patches and it's helping soothe all of this.

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